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Hugh H. Hussey, MD

JAMA. 1974;230(6):881.

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In recent issues of the ARCHIVES OF OPHTHALMOLOGY and the ARCHIVES OF NEUROLOGY, Kennerdell et al¹ and Hackett et al,² respectively, have reported cases in which what appeared initially to be optic neuritis was the premonitory symptom of a serious underlying disease.

The patient described by Kennerdell and his colleagues was a 47-year-old woman who first complained of blurred vision in the right eye accompanied by pain on motion of the globe and deep retro-orbital discomfort. Her visual acuity in the affected eye was best corrected to 20/400, and the optic disc was hyperemic. Based on a presumptive diagnosis of optic neuritis, corticosteroid therapy was administered and led to dramatic visual improvement. Relapse followed within a month, but resumption of corticosteroid therapy again was effective.

About a year later, visual acuity was again impaired, now bilaterally, and there was deep suborbital pain on the right. Skull roentgenograms and . . . [Full Text PDF of this Article]

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