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Radionuclide Detection of Metastatic Calcification
A. G. Richards, MD, FRCP
Royal Jubilee Hospital Victoria, British Columbia
JAMA. 1975;231(13):1339.
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To the Editor.—
The article "Radionuclide Detection of Diffuse Interstitial Pulmonary Calcification" (230:992, 1974) was of special interest to me since it coincided with my report of a similar case in the Journal of Nuclear Medicine (15:1057, 1974).
My patient, who had hypercalcemia, hyperphosphatemia, and renal failure in association with a poorly differentiated malignancy of the bone marrow showed a dense and diffuse uptake of technetium 99m-labelled polyphosphate throughout the lungs and stomach during the course of a bone scan. Calcification of the stomach and kidneys was proven histologically on tissues removed through simple biopsy procedures but biopsy of the lung (a more formidable procedure) did not seem justified. More recently I have observed another patient, a woman of 33, with hypercalcemia, hyperphosphatemia and renal failure due to vitamin D intoxication. She, too, showed diffuse uptake of99mTc-labelled polyphosphates throughout the lungs during a bone scan and had histologically
. . . [Full Text PDF of this Article]
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