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B. H. KEAN, MD
New York Hospital-Cornell Medical Center New York

JAMA. 1975;231(6):569.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

The article, "Typhoid Hepatitis," by Ramachandran et al (230:236, 1974) is another in the series creating confusion about the nature of hepatitis. Unhappily, the term is used to describe two different entities: focal lesions that may be seen in a single lobule or may be large enough to destroy several lobules, and diffuse lesions involving virtually all lobules. The focal lesions are seen in leprosy, tuberculosis, and amebiasis, and have clinical evidence of hepatic insufficiency only rarely. Examples par excellence of diffuse lesions are those seen in viral hepatitis and yellow fever.

Amebic involvement of the liver is a focal lesion, single or multiple, small or large, and there is no such entity as diffuse amebic hepatitis. The lack of evidence for amebic hepatitis, presumably a diffuse lesion, has not prevented the publication of a series of articles describing it by Ramachandran and Doxiades.

For two decades, Dr. . . . [Full Text PDF of this Article]

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