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  Vol. 231 No. 6, February 10, 1975 TABLE OF CONTENTS
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No Statistical Refuge for the {alpha}1 Antitrypsin-Deficient Smoker

Kenneth M. Moser, MD; Thomas C. Kravis, MD

JAMA. 1975;231(6):625-627.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

All would agree that the best solution to the near-epidemic problem of chronic obstructive pulmonary diseases is to learn how to prevent them. The great "antismoking wars" of the 1960s have proved inconclusive, and the combatants are obscured by an increasingly heavy layer of cigarette smoke. While the battle continues, the ultimate weapon— threat of death and disability—has been used; and without the decisive effect hoped for. To what weapons do we turn now? There are two of major potential. One is discovery of the causes of chronic obstructive lung diseases (COPD) (subtitle: how cigarette smoking does its deadly work). Such discovery may permit the institution of prophylactic alternatives acceptable to people bent on puffing away. The other weapon, less sweeping in impact, is the identification of persons in whom cigarette smoking will induce obstructive lung disease. A great refuge of the smoker is the statistical thicket. Since many smokers . . . [Full Text PDF of this Article]


Author Affiliations

University of California San Diego



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