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John W. Pickren, MD

JAMA. 1975;231(9):969-971.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IN CURATIVE resections for carcinoma of the colon, rectum, and anus, the extent of metastasis of cancer cells into the resected lymph nodes is an important factor in predicting the eventual outcome in terms of whether the cancer will reappear as a distant metastasis. For example, the 5-year cure rate for surgical resection is twice as high in patients with colon carcinoma that has not metastasized to the resected lymph nodes, as the rate in those patients with colon carcinoma that has metastasized to the resected lymph nodes. When the regional lymph nodes are not involved, approximately 70% to 80% of patients undergoing a curative type of resection will be free of disease for a period of five years; but when the regional lymph nodes contain metastatic foci of cancer, the curative operative procedure will yield a disease-free period of five years in only 20% to 40% of the patients. . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Pathology, Roswell Park Memorial Institute, Buffalo, NY.

Footnotes
Reprint requests to 666 Elm St, Buffalo, NY 14203 (Dr. Pickren).

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