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Combination of Preoperative Irradiation and Surgery

Kenneth R. Stevens, Jr., MD; William T. Moss, MD

JAMA. 1975;232(11):1158-1160.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IT HAS been estimated that at least 60,000 patients die each year from our inability to control cancer while it is still localized at or near its site of origin.¹ This disappointing failure to control local cancer with surgery alone, or with radiation therapy alone, has led to many clinical trials that combine these two modalities. In their search for optimum sequencing and technique, proponents of combined forms of therapy have been acutely aware of the fact that halftreatment with radiotherapy and half-treatment with surgery can rarely be combined to produce control rates equal to the more radical application of either method alone. Because of this fact, it is understood that the combination of the two methods usually calls for high-dose radiotherapy and a surgical procedure not too different from that recommended if no radiotherapy has been given.

Rationale of Combined Radiation Therapy and Surgery

There are a variety . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Radiation Therapy, University of Oregon Medical School, Portland.

Footnotes
Reprint requests to Department of Radiation Therapy, University of Oregon Medical School, 3181 SW Sam Jackson Park Rd, Portland, OR 97201 (Dr. Stevens).

Edited by Z. Danilevicius, MD, Senior Editor.

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