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Corticosteroid TherapyI. Pharmacological Properties and Principles of Corticosteroid Use
David H. P. Streeten, MB, D Phil, MRCP
JAMA. 1975;232(9):944-947.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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SINCE cortisone and corticotropin first became available more than 25 years ago, these agents, and particularly the newer synthetic corticosteroids, have established an important place for themselves in the therapy of a wide variety of disorders falling within the purview of virtually every branch of medical practice. Surprisingly, however, there is still uncertainty about the role of steroid therapy in several specific disease states. There are also some important recent advances of a practical nature that make it worthwhile to review the modern use of steroid therapy in clinical practice.
PHARMACOLOGICAL PROPERTIES
Corticosteroids have widely differing actions on the tissues and fluids of the body, and many of their effects may be considered therapeutically valuable in one patient and unwarranted side effects in another. Thus, the effect of raising blood glucose levels may be an important reason for using a glucocorticoid in a patient with adrenal insufficiency or, temporarily, in
. . . [Full Text PDF of this Article]
Author Affiliations
From the Section of Endocrinology, Department of Medicine, State University of New York Upstate Medical Center, Syracuse, NY.
Footnotes
Reprint requests to Department of Medicine, Upstate Medical Center, 750 E Adams St, Syracuse, NY 13210 (Dr. Streeten).
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