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Irwin L. Stoloff, MD
Jefferson Medical College Philadelphia

JAMA. 1975;233(11):1165.

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In Reply.—

Drs Gueldner and Lawrence raise the question of operability on patients with an endoscopic biopsy-demonstrated cancer and state that they have observed seven long-term, clinically cancer-free patients among that group. My observations suggest that, in terms of long-term survival, a better discriminant could be obtained in their series were they to isolate all cancers located within the main stem bronchi (227:299, 1974). Using the date of roentgenographic detection as the date of entry into the study, the five-year survival for such persons was 2%. This meant one long-term survivor of 132 persons with main stem lesions, and this patient lived five years from the date of x-ray diagnosis, without a surgical resection. When one looks at persons with tumors distal to the main stem bronchus, such as those in peripheral bronchi, with bronchoscopic abnormalities other than the detection of a tumor, or persons with normal bronchoscopic findings, the . . . [Full Text PDF of this Article]

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