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JAMA. 1975;234(11):1101-1108.

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New studies tighten link between herpesvirus, cervical cancer

The long-smouldering suspicion that genital infection with herpes simplex virus type 2 (HSV-2) is venereally transmitted and carries with it an enhanced risk of cervical cancer, carcinoma in situ, and lesser uterine dysplasias and "atypias" has now become a virtual certainty. This was made clear in two back-to-back presentations at the recent conference on sexually transmitted diseases, which was sponsored by the New York Academy of Medicine.

Speaking for the group under André Nahmias, MD, professor of pediatrics and associate professor of preventive medicine and community health at Emory University, William E. Josey, MD, associate professor of gynecology and obstetrics told the conference: "Ultimate proof of causality may necessitate a comparison of the rate of development of cervical neoplasia in two groups of women: one group immunized against HSV-2 infection and the other unprotected." Dr Josey confirmed that in the prospective . . . [Full Text PDF of this Article]

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