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A Case With Unusual Clinical Manifestations

Tanomsri Srichaikul, MD, MSc; Amnuay Thithapandha, PhD; Somchart Lochajaya, MD; Kriengkrai Akarawong, MD; Kobchai Pauvilai, MD

JAMA. 1975;234(11):1164-1166.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

PLASMA cell leukemia is a very rare form of immunocytic dyscrasia. Clinical course, laboratory findings, therapy, and prognosis of the disease were discussed recently by Pruzanski et al,¹ who reviewed 57 cases reported in the literature during the last 20 years. The clinical picture varies from the terminal leukemic stage of an otherwise classical multiple myeloma to a fulminating course of acute leukemia. On initial examination, our patient had episodes of vascular hyperactivity and high-output cardiac failure. Blood histamine level was found to be strikingly elevated with each episode. To our knowledge, this clinical manifestation has not been reported previously.

Report of a Case

A 27-year-old man was admitted on April 7, 1970, with a four-month history of intractable ascites and congestive cardiac failure. Physical examination showed an orthopneic young man with a blood pressure of 100/70 mm Hg; pulse, 96 beats per minute; respirations, 26/min; temperature, 36.8 C . . . [Full Text PDF of this Article]

Author Affiliations
From the departments of medicine (Drs. Srichaikul, Lochajaya, Akarawong, and Pauvilai) and pharmacology (Dr. Thithapandha), Mahidol University, Bangkok, Thailand.

Footnotes
Reprint requests to Faculty of Medicine, Ramathibodi Hospital, Rama VI Road, Bangkok 4, Thailand (Dr. Srichaikul).

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