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Elevated T3 and T4 Levels With Normal TSH Level

Harris C. Taylor, MD

JAMA. 1975;234(12):1253-1255.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THYROTOXICOSIS in the prepubertal patient is almost invariably due to Graves disease. The recent report of Popma et al¹ underscores, however, the responsibility of the solitary hyperfunctioning nodule for clinically significant hyperthyroidism in the pediatric patient. To our knowledge, this communication presents the second chemically documented example of hyperthyroidism due to a benign solitary hyperfunctioning adenoma in a child, and the first to produce both excessive thyroxine (T₄) and triiodothyronine (T₃) levels in the face of a normal serum thyroid-stimulating hormone (TSH) level.

Report of a Case

An 11 1/2-year-old girl was first seen in referral during December 1972. A previous physical examination in April 1971 had been normal. In February 1972, her pediatrician noted a right thyroid nodule. History disclosed some increase in sweating and a tendency to use fewer blankets at night. Her mother observed an increased irritability and a preference for the family room . . . [Full Text PDF of this Article]

Author Affiliations
From the Ohio Permanente Medical Group and the Kaiser Foundation Hospital, Cleveland Heights, Ohio.

Footnotes
Reprint requests to Ohio Permanente Medical Group, 50 Severance Circle, Cleveland Heights, OH 44118 (Dr Taylor).

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