To the Editor.—
An answer to a query regarding "bulk producers" as anorectic agents (230:901, 1974) unintentionally may have generated the impression that these compounds "work" because, in forming a large colloidal mass in the stomach and "by slowing the course of a meal," a sensation of satiety is produced.
I believe that this impression should be corrected for two reasons. First, various bulk producers of the methylcellulose family have no proved anorectic effect. Second, the express statement in THE JOURNAL that these products are effective plays into the hands of promoters of dubious diet schemes who advertise a wide variety of useless pills containing methylcellulose.
In such diet regimens, 0.5- to 1.0-gm methylcellulose tablets are to be swallowed with a glass of water one-half hour before meals. We have put this suggestion to a test in several instances. In one representative subject, the x-ray films (Figure) demonstrate that gastric
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