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Melvin Yudis, MD; John J. Meehan, MD

JAMA. 1976;235(18):2000.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

MANY DRUGS can precipitate a syndrome resembling systemic lupus erythematosus (SLE). The most common are hydralazine hydrochloride, procainamide hydrochloride, and various anticonvulsants. To our knowledge, only two previous cases of quinidine-related lupus have been recorded.^1,2 Our case involved the musculoskeletal system and the kidneys.

Case Report

A 49-year-old woman was first admitted to Holy Redeemer Hospital in August 1970 with a diagnosis of rheumatic mitral stenosis with atrial fibrillation. At that time, the antistreptolysin O titer, hemoglobin value, blood cell count, and urinalysis results were normal. Digoxin therapy was started with a dosage of 0.25 mg daily. The patient was also receiving warfarin sodium (Coumadin), 7.5 mg daily, and meprobamate, 200 mg four times a day. Her rhythm reverted to normal with digoxin therapy.

The patient remained well until July 1973, when she was readmitted because of recurrence of atrial fibrillation with an uncontrolled ventricular response. Her treatment consisted . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Medicine, subsections of nephrology (Dr Yudis) and cardiology (Dr Meehan), Holy Redeemer Hospital, Meadowbrook, Penn.

Footnotes
Reprint requests to 1231 York Rd, Abington, PA 19001 (Dr Yudis).

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