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Gastroduodenal Involvement, With Pain, Vomiting, and Weight Loss
Azam Ansari, MD;
Quentin Anderson, MD;
Emerson Hoppes, MD;
Earl Henrikson, MD
JAMA. 1976;235(18):2013-2014.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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History
A 52-year-old woman complained of epigastric pain, early satiety, post-prandial vomiting, and weight loss of six months' duration. An upper gastrointestinal roentgenographic series was performed (Fig 1 and 2). Two years earlier she had undergone abdominal surgery for a related illness.
Diagnosis
Crohn disease of the stomach and duodenum.
Comment
Figures 1A and B demonstrate rigidity, narrowing, and irregularity of the antrum, pylorus, and duodenum. A "cobblestone" or "string of pearls" appearance of the mucosa in the body of the stomach is clearly seen in Fig 1C and D and 2. Figure 3 shows pseudopolypoid nodulation of the mucosa in the resected specimen of the stomach that closely parallels with the roentgenographic pattern shown in Fig 1C and D. Figure 4 illustrates the histologic appearance, showing foci of chronic inflammatory reaction in the submucosa. Granulomas are easily identified and contain many giant cells. No central caseation nor acid-fast bacilli
. . . [Full Text PDF of this Article]
Author Affiliations
From the departments of medicine (Dr Ansari), radiology (Dr Anderson), and surgery (Drs Hoppes and Henrikson), Metropolitan Medical Center, Minneapolis.
Footnotes
Reprint requests to Suite M04, 825 S Eighth St, Minneapolis, MN 55404 (Dr Ansari).
Edited by Z. Danilevicius, MD, Senior Editor.
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