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Robert R. Siroty, MD

JAMA. 1976;235(23):2521-2522.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE ENTITY of quinine-induced purpura is well recognized and has been described many times. On several occasions, its relation to the ingestion of cocktails mixed with quinine water—so-called cocktail purpura or gin-and-tonic purpura—has been reported.^1,2 We recently encountered a well-disguised case with potentially serious consequences.

Report of a Case

A 27-year-old woman was admitted to Dover General Hospital in January 1973 with chills and the rapid development of purpura, including buccal mucous membrane hemorrhages. Platelet count was 1,000/cu mm; other laboratory data were normal. The patient had had a recent episode of acute gastroenteritis but was otherwise well. She denied taking any drugs except a mixture of chlorpheniramine maleate, aspirin, and caffeine (Coricidin) and aspirin and denied drinking quinine-containing cocktails.

Bone-marrow examination revealed abundant numbers of normal-appearing megakaryocytes and normal myeloid and erythroid elements.

The patient was treated with prednisone (40 mg/day) and had a rapid and sustained rise . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Hematology, Dover General Hospital, Dover, NJ.

Footnotes
Reprint requests to 77 Union Street, Dover, NJ 07801.

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