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Syphilis Therapy Still Imperfect
Fred Levit, MD
JAMA. 1976;236(19):2213-2214.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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The articles by Tramont and by Mohr et al that appear in this issue of THE JOURNAL (pp 2206 and 2208, respectively) may call into serious question our present methods of treating all but primary syphilis. A patient with the spirochetemia of secondary syphilis must be assumed to have had spirochetes delivered to almost all of his tissues. It has also been assumed that the treatment schedules now used for secondary syphilis would be adequate treatment to prevent late syphilis. This, it now appears, may not be so.
Of course, finding that penicillin G benzathine does not reach the cerebrospinal fluid (CSF) is not exactly the same as saying that it has failed to cure the disease. Similarly, finding some spirochetes in the CSF is not exactly the same as saying that the patient has active or progressive disease. Nevertheless, no physician who now has the responsibility of treating syphilis
. . . [Full Text PDF of this Article]
Author Affiliations
Northwestern University Chicago
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