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Tetracycline
Robert S. Bart, MD
New York University School of Medicine New York
JAMA. 1976;236(4):344.
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To the Editor.—
I am writing in reference to the commentary entitled "The Treatment of Amebiasis: A Recurrent Agony," by B. H. Kean, MD (235:501, 1976). In his discussion, the author states that "tetracycline, originally advocated at a dosage of 2 gm daily for 14 days, cannot be used at that level without considerable toxic reaction, and a dosage of 1 gm daily for seven days is hardly curative." I do not wish to get involved in a discussion of the treatment of amebiasis, since my experience in treating that disease is so limited that I cannot speak with any authority on the subject. However, it would seem inappropriate to abandon the use of tetracycline, in the dosage of 2 gm/day for 14 days, solely on the grounds that it is too toxic. Baer and co-workers (Arch Dermatol 105:608, 1972) have treated severe conglobate acne with doses of 2 gm/day
. . . [Full Text PDF of this Article]
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