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An Unusual Presentation of Malignant Melanoma

Stephen L. Goldman, MD; Erich W. Pollak, MD; Earl F. Wolfman, Jr, MD

JAMA. 1977;237(1):52.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

GASTRIC metastases are frequently found during autopsy of patients with malignant melanoma. However, few of these have been diagnosed during life. The following report is concerned with a patient with clinical and radiological findings suggestive of gastric ulcer. A definitive diagnosis of metastatic melanoma was made only six weeks later, when disseminated disease elsewhere was already present.

Report of a Case

A 46-year-old, essentially healthy laborer complained to his family physician of crampy midepigastric pain, weakness, and weight loss. An upper-gastrointestinal radiological study was performed and showed an active gastric ulcer. Ulcer diet, antacids, and anticholinergics were prescribed and were followed by transient relief. Within six weeks of onset, bluish subcutaneous nodules developed on the anterior aspect of the patient's chest and arms. At the same time a pathological fracture of the spinous process of C-7 and melanuria developed. Biopsy of one subcutaneous nodule led to the histologic diagnosis of . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Surgery, University of California, Davis, and from the Sacramento Medical Center, Sacramento, Calif.

Footnotes
Reprint requests to 1630 Tamarack Lane, Davis, CA 95616 (Dr Pollak).

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