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Lt Col Raymond L. Garcia, MC; Maj Joseph T. Backe, MC

JAMA. 1977;237(15):1598-1599.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE ASSOCIATION of systemic amyloidosis with monoclonal-component or M-component diseases such as multiple myeloma, Waldenström macroglobulinemia, lymphomas, and leukemia is well known. The purpose of this communication is to present a case of aleukemic chronic lymphocytic leukemia with an IgM paraprotein M-component associated with primary systemic amyloidosis in which IgM was found in the skin lesions on immunofluorescent staining.

Report of a Case

A 52-year-old man came to our clinic with a five-month history of an asymptomatic generalized eruption of waxy papules. The eruption was preceded by two months of a gradual progression of numbness and burning in all extremities and a weakness in both hands.

On physical examination, numerous smooth, skin-colored, translucent papules (2 to 4 mm), several with a hemorrhagic component, were noted on the elbows, knees, calves, shins, wrists, buttocks, and ventral aspect of the upper extremities (Fig 1). There were two areas of linear purpura on . . . [Full Text PDF of this Article]

Author Affiliations
USAF; USAF

From the Dermatology Service, Wilford Hall USAF Medical Center, Lackland Air Force Base, Tex.

Footnotes
Reprint requests to Dermatology Service, Wilford Hall USAF Medical Center, Lackland Air Force Base, TX 78236 (Dr Garcia).

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