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James O. Armitage, MD; Raymond F. Sheets, MD

JAMA. 1977;237(21):2323-2324.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THROMBOCYTOPENIC purpura has been reported secondary to a multiplicity of causes.¹ However, idiopathic thrombocytopenic purpura (ITP), in relation to infectious diseases other than viral illnesses, is unusual. We report two cases where ITP developed with the onset of histoplasmosis.

Report of Cases

CASE 1.—

A 41-year-old woman was referred to the University of Iowa Hospitals on July 3, 1970, with a two-week history of fevers, chills, headache, nonproductive cough, and a 7-kg weight loss. She had failed to respond to oral antibiotic therapy. She had been in good health prior to the onset of the aforementioned symptoms, and there was no antecedent history of easy bleeding, bruising, or hematologic abnormality. The patient appeared severely ill and was febrile. Neither lymphadenopathy nor hepatosplenomegaly was found. Pulmonary and cardiovascular examination results were unremarkable. Petechiae and ecchymoses were not observed. Initial laboratory studies included a WBC count of 7,400/cu mm, with 81% . . . [Full Text PDF of this Article]

Author Affiliations
From the Division of Hematology-Oncology, Department of Internal Medicine, College of Medicine, the University of Iowa and University Hospitals, Iowa City (Drs Armitage and Sheets).

Footnotes
Reprint requests to Division of Hematology, Department of Internal Medicine, University of Nebraska Medical Center, 42nd and Dewey, Omaha, NB 68105 (Dr Armitage).

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