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1. Background and Use

James L. Tullis, MD

JAMA. 1977;237(4):355-360.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE INCREASING use of human serum albumin, which recently has threatened to stress the usual annual supply and to add considerably to health care costs, prompted a cooperative study in early 1975 between the federal government and the private sector. This led to the development of three projects: (1) A workshop was convened in Bethesda, Md, under joint sponsorship of the Division of Blood Diseases and Resources, National Heart and Lung Institute, and the Division of Blood and Blood Products, Bureau of Biologics. This meeting in February 1975 defined the present state of knowledge of the structure, synthesis, and function of albumin and reviewed in depth its current clinical use. The proceedings were subsequently published.¹ (2) Recommendations were formulated on areas needing further basic or applied research. (3) Guidelines for the appropriate clinical use of albumin were proposed and are currently being circularized to concerned persons for comment.

Although . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Medicine, New England Deaconess Hospital; the Department of Medicine, Harvard Medical School; and the Center for Blood Research, Boston.

Footnotes
This comprehensive review of the biochemistry, physiology, and clinical use and abuse of albumin is based on the Proceedings of the Workshop on Albumin sponsored by the Division of Blood and Blood Products, Bureau of Biologics; the Division of Blood Diseases and Resources, National Heart and Lung Institute; and the National Institutes of Health, Feb 12 through 14, 1975.

The author has had an exchange of views on this text with representatives of the Council of Europe Coordinated Blood Transfusion Research Programme (1976).

The 59 contributors whose work comprises the substance of this report are listed on page 359. The full text of each article is available in a bound volume published by the National Institutes of Health.

Reprint requests to Bldg 31, Room 4A-08, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20014 (Dr Anthony René).

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