 |
|
Photodye Herpes Therapy—Cassandra Confirmed?
Richard S. Berger, MD;
Christopher M. Papa, MD
JAMA. 1977;238(2):133-134.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
|
|
|
THE DERMATOLOGISTS attending the meeting of the Noah Worcester Dermatologic Society (Hollywood, Fla, March 2, 1976) reacted as though a live grenade had been tossed into their midst. They had just heard a report that provided clinical support for the speculation that photodye therapy for herpes simplex infections might be carcinogenic.1,2 Also, they were reminded that recent studies questioned the efficacy of this therapy.3-5 Neither suggestion was well received by the audience. Burdened by long suffering patients and the ever increasing incidence of recurrent herpes simplex infections, these practitioners sought any reasonable treatment. They were encouraged by early reports of photodye treatment because of its readily available components and because its apparent efficacy could be explained in terms of molecular alterations in viral DNA infective units.6,7
Photoinactivation therapy is achieved in a two-step process. Painted on the unroofed vesicles, a heterotricyclic dye such as neutral red or
. . . [Full Text PDF of this Article]
Author Affiliations
College of Medicine and Dentistry of New Jersey Rutgers Medical School Greenbrook
From the Department of Medicine, Division of Dermatology, College of Medicine and Dentistry of New Jersey, Rutgers Medical School, Greenbrook, NJ.
Footnotes
Reprint requests to 501 George St, New Brunswick, NJ 08903 (Dr Berger).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
|
