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Recent Developments in Fuel Metabolism

Norbert Freinkel, MD

JAMA. 1978;239(18):1868-1872.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IN HIS 1913 address to the New York Academy of Medicine, Lusk¹ defined nutrition as follows:

The workshops of life require fuel to maintain them, and a necessary function of nutrition is to furnish fuel to the organism that the motions of life continue. Furthermore, the workshops of life are in a constant state of partial breaking down and materials must be furnished to repair the worn-out parts. In the fuel factor and the repair factor lie the essence of the science of nutrition.

Benedict² extended the definition to include the traffic in endogenous as well as exogenous fuels. Thus, in the 1915 account of his study of prolonged fasting, he wrote:

In the normal life of man, the demands for nutrition are usually met by periodic feeding. When the demands are not met, body reserves must be drawn upon.... It is to study these problems that observations . . . [Full Text PDF of this Article]

Author Affiliations
From the Center for Endocrinology, Metabolism, and Nutrition and the Departments of Medicine and Biochemistry, Northwestern University, The Medical School. Chicago

Footnotes
Adapted from the Plenary Lecture read before the Western Hemisphere Nutrition Congress V, Quebec, Aug 15, 1977.

Reprint requests to Center for Endocrinology, Metabolism, and Nutrition, Northwestern University, The Medical School, 303 E Chicago Ave, Chicago, IL 60611 (Dr Freinkel)

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