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R. L. Myerowitz, MD; M. Pietruszka, MD; E. L. Barnes, MD
Presbyterian-University Hospital Pittsburgh

JAMA. 1978;239(5):403.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

Primary angiosarcoma of the breast is a rare neoplasm characterized by its rapid growth, large size, and frequent recurrences with metastasis. Long-term survival is rare.^1-3 In support of recent reports suggesting multimoduality therapy^4,5 (237:2605, 1977) for sarcomas, we wish to relate the clinical and pathologic features of a patient who survived for four years after diagnosis.

Report of a Case.—

In April 1973, at the age of 43 years, the patient came to us with a right breast mass; the biopsy specimen showed angiosarcoma. Therapy consisted of a simple mastectomy followed postoperatively by vincristine and cyclophosphamide chemotherapy. The patient did well until October 1975 when she came for her second admission because of iron deficiency anemia. Her barium enema showed a persistent narrowing of the colon near the hepatic flexure. Selective celiac and superior mesenteric arteriograms showed metastatic angiosarcoma in the distal duodenum. A questionable . . . [Full Text PDF of this Article]

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