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Nitroprusside Therapy for a Patient With a Pheochromocytoma
Ace Lipson, MD;
Tah-Hsiung Hsu, MD;
Barbara Sherwin, MD;
Glenn W. Geelhoed, MD
JAMA. 1978;239(5):427-428.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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WE DESCRIBE a patient in hypertensive crisis from a pheochromocytoma, in whom sodium nitroprusside was used without adrenergic blockers, and subsequently was administered for a one-week period in conjunction with blockers to achieve preoperative and ultimately intraoperative blood pressure control. We believe this represents the most extensive experience with this drug in one patient with this condition.
Report of a Case
A 32-year-old woman was transferred to the George Washington University Hospital Intensive Care Unit from another hospital, with uncontrolled hypertension six hours after cesarean section. The patient had a history of labile hypertension and diet-controlled diabetes. She was hypertensive during her first pregnancy, miscarrying at six months.
During the current pregnancy, blood pressure became 140/90 mm Hg, and occasional flushing, pedal edema, and proteinuria occurred. At 32 weeks, she was admitted with a blood pressure of 220/140 mm Hg, unchanged by diazepam and bed rest. Despite methyldopa therapy, 500
. . . [Full Text PDF of this Article]
Author Affiliations
From the Department of Medicine (Drs Lipson and Hsu), Johns Hopkins University, Baltimore, and the Departments of Medicine (Drs Lipson and Sherwin) and Surgery (Dr Geelhoed), George Washington Hospital, Washington, DC.
Footnotes
Reprint requests to the Johns Hopkins Hospital, Baltimore, MD 21205 (Dr Lipson).
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