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Florid Cushing's Syndrome and Hirsutism Induced by Desoximetasone
Thep Himathongkam, MD;
Puangpen Dasanabhairochana, MD;
Ninlawan Pitchayayothin, BSc;
Arporn Sriphrapradang, BSc
JAMA. 1978;239(5):430-431.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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CORTICOSTEROIDS have been used topically since 1952 with minimal side effects compared with corticosteroids administered systemically. However, substantial amounts of topically applied corticosteroids may be absorbed percutaneously and cause adrenal suppression.1 It is surprising that few cases of Cushing's syndrome induced by use of topical steroids have been reported, and those were in children. Cushing's syndrome and hirsutism induced by topically applied desoximetasone (Topicorte) was diagnosed in a woman.
Report of a Cas
A 45-year-old woman was referred to Ramathibodi Hospital for examination for Cushing's syndrome. Two years before admission, hair growth had developed on her face and back to an extent that she had to shave every other day. One year before admission, she experienced reddish striae on her skin and bruising with slight contact. Her weight had increased by 10 kg during the past nine months. She had had psoriasis since age 17 years, and the lesions
. . . [Full Text PDF of this Article]
Author Affiliations
From the Department of Medicine, Faculty of Medicine, Ramathibodi Hospital and Ramathibodi Research Center, Mahidol University, Bangkok, Thailand.
Footnotes
Reprint requests to Department of Medicine, Ramathibodi Hospital, Rama VI Rd, Bangkok 4, Thailand (Dr Himathongkam).
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