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Sheldon Greenfield, MD; M. Colin Jordan, MD

JAMA. 1978;240(13):1388-1393.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ENLARGED lymph nodes occur in many conditions, either as a reaction to a local inflammatory process or associated with a systemic disease whose central focus is not in the lymph system. In some patients enlarged nodes are the initial or the most prominent manifestation of whatever disease is present and are the starting point for investigation. The algorithm presented here develops guidelines for evaluation of lymph node enlargement of the primary or secondary type.

Scope and Limitations

This algorithm is designed to be applied only to adolescents and adults, because a different array of diseases underlies enlarged lymph nodes in infants and children. It does not include therapy for any of the conditions detected. Following the model of protocols or clinical algorithms for primary care, it does not include diagnostic evaluation of rare diseases. On the other hand, nonspecific findings are included to alert the reader to consider more remote . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Medicine, UCLA School of Medicine (Drs Greenfield and Jordan) and UCLA School of Public Health (Dr Greenfield), Los Angeles.

Footnotes
Reprint requests to Department of Medicine, UCLA School of Medicine, Center for the Health Sciences 42-170, Los Angeles, CA 90024 (Dr Greenfield).

Edited by M. Therese Southgate, MD, Deputy Editor.

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