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A. Wise, PhD
University of Isfahan Isfahan. Iran

JAMA. 1978;240(19):2045-2046.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

Because chromiumdeficient rats exhibit a diabetic state that is easily corrected by a single dose of chromium (III), it is natural to wonder whether chromium deficiency may be a cause of human diabetes. It appears that a chromium complex facilitates the action of insulin.¹ A single dose of 250 µg of chromium (III) was found to improve glucose tolerance in some cases of infant malnutrition, and many recently published textbooks state that there are beneficial effects of chromium (III) supplementation in patients who have poor glucose tolerance. This information is based on the results of several experiments in the United States, and it was decided to repeat them in Iran.

Nine hospitalized patients with abnormal fasting glucose levels (106 to 378 mg/dl) were given chromium (1 mg/day as Cr Cl₃) for six days. Previous reports have discussed the effect of chromium only on glucose tolerance, . . . [Full Text PDF of this Article]

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