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Propoxyphene
JAMA. 1979;241(16):1689.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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PROPOXYPHENE (Darvon) is an analgesic widely prescribed for the relief of mild to moderate pain. For example, it is frequently employed to decrease postoperative pain. It should not be used for chronic pain because it has a low but nevertheless occasional addicting property. Propoxyphene does not have an anti-inflammatory action such as aspirin possesses and therefore is not the preferred drug when both pain relief and suppression of inflammation are the therapeutic goals. Even with its limitations, however, it is judged by most physicians to be a useful product to have available in their therapeutic armamentarium.
Propoxyphene was first marketed 21 years ago, and since that time more than 20 billion doses have been prescribed. This vast experience, documented in more than 850 publications, has given prescribers a thorough appreciation of the drug's effectiveness, toxicity, interaction with other drugs, and potential for abuse. The effectiveness of propoxyphene has been studied
. . . [Full Text PDF of this Article]
Footnotes
From the Division of Scientific Publications, American Medical Association, Chicago.
Reprint requests to Division of Scientific Publications, American Medical Association, 535 N Dearborn St, Chicago, IL 60610 (Dr Barclay).
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