
Efficacy of Instant Glucose
Harvey M. Rosenbaum, MD
Diabetes Association of Greater Cleveland St Luke's Hospital Case Western Reserve University
Saul M. Genuth, MD
Saltzman Institute for Clinical Investigation Mount Sinai Hospital of Cleveland Case Western Reserve University
Gerald T. Kent, MD
University Suburban Health Center Case Western Reserve University
O. Peter Schumacher, MD, PhD
Cleveland Clinic Foundation Case Western Reserve University
Ralph G. Wieland, MD
St Luke's Hospital Case Western Reserve University Cleveland
JAMA. 1979;241(18):1890.
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To the Editor.—
Gunning and Garber have shown in their article "Bioactivity of Instant Glucose: Failure of Absorption Through Oral Mucosa" (240:1611, 1978) that buccal absorption of glucose from instant glucose did not occur in normal, nondiabetic volunteers, but that 88% of a swallowed dose of instant glucose was absorbed by intestinal hydrolysis during a 30-minute interval in the same volunteers. They then stated that patients in hypoglycemic coma might possibly have a depressed gag reflex and either aspirate the instant glucose or puddle it in the oropharynx.
They therefore conclude that instant glucose may be dangerous or may not work under certain circumstances, and they suggest that "other treatment may be more appropriate."
The Diabetes Association of Greater Cleveland has produced and distributed instant glucose since 1967. It was primarily designed for the patient to carry on his person. If the patient feels impending hypoglycemia or friends note unusual
. . . [Full Text PDF of this Article]
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