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Primary Mesenteric Vein Thrombosis Associated With Antithrombin III Deficiency
Capt Frank R. Arko, MC;
Comdr C. Thomas Jewell, MC;
Lt Comdr Paul Dainer, MC;
Capt William A. J. MacLeod, MC
JAMA. 1979;242(21):2324-2325.
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PRIMARY mesenteric vein thrombosis associated with hereditary antithrombin III (AT III) deficiency has recently been reported as a new clinical entity.1 Primary mesenteric vein thrombosis is a result of abnormal coagulation, whereas most cases of mesenteric vein occlusions are secondary to some other disease process.
This case report of a patient who had segmental infarction, recurrent infarction, postresection morbidity, and clinical evidence of hypercoagulability depicts and reemphasizes the diagnostic and therapeutic difficulties encountered by the surgeon who must deal with this problem.
Report of a Case
A 47-year-old man was first seen with a six-day history of midepigastric pain and nausea. Pain was strikingly intensified by food ingestion.
History disclosed deep-vein thrombosis in the left leg, for which the patient had received anticoagulant therapy three years previously. Family history disclosed that the patient's father died of peritonitis, which, according to the patient, was secondary to a "blood clot to
. . . [Full Text PDF of this Article]
Author Affiliations
USN; USN; USN; USN
From the Surgery Service (Drs Arko, Jewell, and MacLeod), Internal Medicine Service (Dr Dainer), and the Clinical Investigation Center, Naval Regional Medical Center, San Diego.
Footnotes
The views expressed herein are those of the authors and do not necessarily reflect the views of the US Navy or the Department of Defense.
Reprint requests to Surgery Service, Naval Regional Medical Center, San Diego, CA 92134 (Dr MacLeod).
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