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Sharon Grundfest, MD; Ezra Steiger, MD

JAMA. 1980;244(15):1701-1703.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

HOME parenteral nutrition (HPN) has revolutionized the treatment of formally fatal intestinal problems in much the same way that renal dialysis has affected the outlook for patients with chronic renal failure. Until recently, patients with severe malabsorption syndromes or massive small-bowel resections occasioned by vascular accidents, inflammatory bowel disease, or radiation enteritis were doomed to repeated hospitalizations or even death from dehydration, electrolyte abnormalities, and malnutrition. Now such patients may be able to resume a normal nutritional status and a nearly normal life-style.

The idea of providing enough nutritional support by the intravenous (IV) route to achieve positive nitrogen balance should probably be credited to Elman,¹ who in 1948 reported decreased postoperative morbidity in patients given dextrose and protein hydrolysates via peripheral veins. In 1952, Aubaniac² described the technique of percutaneous subclavian venipuncture; however, it remained for Dudrick and colleagues³ to prove that hypertonic solutions of dextrose, . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of General Surgery, Cleveland Clinic Foundation, Cleveland.

Footnotes
Reprint requests to Department of General Surgery, Cleveland Clinic Foundation, Cleveland, OH 44106 (Dr Grundfest).

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