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Etiologic and Prognostic Considerations

Anthony N. DeMaria, MD; Garrett Lee, MD; Ezra A. Amsterdam, MD; Reginald Low, MD; Dean T. Mason, MD

JAMA. 1980;244(8):826-828.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE INCREASING application of coronary angiography to the evaluation of patients with angina pectoris has led to the identification of a group of patients who experience anginal-type chest pain despite the presence of normal coronary artery anatomy by arteriography. Indeed, such patients may constitute up to 20% of those who have undergone elective coronary arteriography for suspected coronary artery disease.¹ Although initially believed to be primarily an affliction of women, the syndrome has been detected with increasing frequency in men and in some studies has been found to be equally prevalent in both sexes. Despite the presence of normal coronary arteries, persons with this syndrome may have major functional impairment. They may often require hospitalization for chest pain evaluation and management and may even present a condition of unstable angina.

Recently, coronary artery spasm has been demonstrated to be responsible for many chest pain syndromes, including variant angina pectoris, . . . [Full Text PDF of this Article]

Author Affiliations
From the Section of Cardiovascular Medicine, University of California School of Medicine, Davis.

Footnotes
This article is one of a series sponsored by the American Heart Association.

Reprint requests to Section of Cardiovascular Medicine, University of California School of Medicine, Davis, CA 95616 (Dr DeMaria).

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