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Harry S. Jacob, MD; Dale E. Hammerschmidt, MD

JAMA. 1981;246(1):25-29.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The Thorndike Model

JAMA:

Dr Jacob, what guidelines did you use to establish your clinical research program?

Jacob:

My own group has been presaged on the type of clinical investigation that culminated in the Thorndike Laboratory at the Boston City Hospital under William Castle, MD, with other greats, such as Maxwell Finland, MD, and Charles Davidson, MD. Within the hospital setting, physicians at the patient's bedside generated insights and trained their students to bring those insights back to the laboratory bench. This approach requires not only a strong subspecialty group, but also an environment in which there are many other subspecialists who have a similar interest in pathogenetic mechanisms of illness.

One of the major problems in research training and clinical investigation is that they have become wildly superspecialized in that people believe that research in their own subspecialty can be done without knowledge of other subspecialties, and this leads . . . [Full Text PDF of this Article]

Footnotes
Reprint requests to Division of Hematology, University of Minnesota School of Medicine, Minneapolis, MN 55455 (Dr Hammerschmidt).

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