To the Editor.—
The material presented in a recent article, "A Run for the Record: Studies on a Trans-American Ultramarathoner" (1981;245: 367), may not reflect the spectrum of biochemical changes occurring because of ultramarathon running.
That article listed blood chemical analyses done for Stan Cottrell three days after he reportedly ran 167.25 miles in 24 hours.
The test results for Cottrell are not nearly as dramatic as results this author conducted for a 28-year-old man the day after the subject's completion of a 100-mile run in 18 hours. The subject had an SGOT value of 1,720 IU/L (normal range, 8 to 33 IU/L); lactic dehydrogenase (LDH), 1,750 IU/L (normal range, 100 to 190 IU/L); and SGPT, 406 IU/L (normal range, 3 to 36 IU/L). No value for creatine phosphokinase was obtained.
These results must be compared with values taken before the race, as follows: SGOT, 84 IU/L; LDH, 394 IU/L;
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