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James S. Lydiatt, MD; Gary E. Hill, MD
Saint Vincent Hospital and Health Center Billings, Mont

JAMA. 1981;246(1):41-42.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

A number of similarities between malignant hyperthermia and heat stroke syndrome exist.^1,2 Disorders of electrolyte balance, renal function, bleeding diathesis, plasma enzyme levels, as well as temperature control are common in both syndromes. We recently treated a case of extreme heat stroke syndrome with intravenous (IV) dantrolene sodium, currently the accepted treatment of choice for malignant hyperthermia,^2,3 with excellent results. The following is a report on that experience.

Report of a Case.—

A 41-year-old 80-kg man was brought to the emergency room with a rectal temperature greater than 42 °C after working in a hot environment before collapsing.

On physical examination, the patient's skin was blotchy, hot, and dry. The respiratory rate was 40 to 45/min, and brachial artery blood pressure was 105/50 mm Hg. Blood was drawn for laboratory studies (Table) followed by rapid intravascular volume expansion (4,000 mL of lactated Ringer's solution over two . . . [Full Text PDF of this Article]

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