This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Hyman J. Roberts, MD

JAMA. 1981;246(2):129-131.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IN A recent editorial on vitamin E therapy, Oski¹ stated: "Fortunately, large doses of this vitamin appear to be tolerated with relative impunity." The purported safety of vitamin E also is repeatedly underscored by physicians in popular health-oriented publications. Wright asserted: "There's never been a case reported of vitamin E toxicity. None of my patients have ever had any problems" (Prevention, February 1978, p 74).

This widely held attitude deserves scrutiny because it could pose a major public health concern. I continue to encounter patients with problems that seem to have been caused or aggravated by self-medication with vitamin E (used here to designate the various tocopherols) in high dosages.^2-4 The more serious ones include the following: (1) thrombophlebitis, pulmonary embolism, or both (my series now exceeds 80 such patients, averaging 62 years of age; four had recurrences on resuming vitamin E treatment); (2) hypertension (22 patients), generally . . . [Full Text PDF of this Article]

Author Affiliations
From the Mannow Research Laboratory, Palm Beach Institute for Medical Research, West Palm Beach, Fla.

Footnotes
Reprint requests to Palm Beach Institute for Medical Research, Inc, 304 27th St, West Palm Beach, FL 33407 (Dr Roberts).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?