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John Henahan

JAMA. 1981;246(20):2309-2311.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Drugs, surgery, and possibly changes in smoking behavior can apparently induce a measurable regression of atherosclerosis and other lesions associated with the onset of heart disease in man and animals, according to a series of reports presented at a recent international congress on lipoproteins and coronary atherosclerosis in Lugano, Switzerland. The meeting was sponsored by the European Atherosclerosis Group and the Fondazione Giovanni Lorenzini, Milan, Italy.

For example, in rhesus monkeys, Robert W. Wissler, MD, PhD, and Dragoslava Vesselinovitch, DVM, of the University of Chicago's Pritzker School of Medicine, found that a combination of cholestyramine resin, a bile acid sequestering agent, and probucol, a cholesterol-lowering drug, both in wide use clinically, produced major regressions in the size of stherosclerotic lesions within a year. The reduction ensued despite the fact that the animals continued to eat the same high-cholesterol diet that had induced the atherosclerosis in the first place.

In the . . . [Full Text PDF of this Article]

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