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Gonococcal Endocarditis With Penicillin-Induced Bone Marrow HypoplasiaRole of Echocardiography
Adam D. Timmis, MB, MRCP;
Marilyn A. Crofts, MB, MRCP;
Jennie Metcalfe, MB, MRCP;
Mark J. Monaghan, MSc;
James Sharp, MB, MRCP;
Graham Jackson, MB, MRCP
JAMA. 1981;246(6):672-673.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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ENDOCARDITIS is a rare complication of gonococcal infection.1 We describe an unusual case in which treatment was complicated by two severe episodes of drug-induced neutropenia. This report emphasizes the important role of echocardiography in the diagnosis and management of endocarditis.
Report of a Case
An 18-year-old woman was admitted with a three-week history of fever, chest pain, and painful swellings on the left index finger and thumb. One week previously, her right knee had been swollen and painful.
Her temperature was 38 °C, splinter hemorrhages were noted, and Osler's nodes were present on the left index finger and thumb. The carotid pulse was regular with a sharp upstroke. The blood pressure was 150/60 mm Hg. There were no signs of heart failure. An ejection systolic murmur and a loud early diastolic murmur were audible over the precordium.
The ECG showed sinus rhythm and widespread nonspecific T-wave flattening. The chest
. . . [Full Text PDF of this Article]
Author Affiliations
From the Departments of Cardiology and Hematology, King's College Hospital, Denmark Hill, London.
Footnotes
Reprint requests to Cardiac Department, King's College Hospital, Denmark Hill, London SE5 9RS, England (Dr Jackson).
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