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Johan Asplund, MD; Gösta Ahlmark, MD; Rolf Gunnarsson, MD; Jan Östman, MD

JAMA. 1981;246(8):870.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

TODAY the diagnosis of insulindependent diabetes mellitus seldom presents problems. However, in two patients recently seen by us, renal glucosuria had been wrongly diagnosed as diabetes mellitus 33 and 51 years earlier. Throughout this period, treatment with long-acting insulin of an unpurified type had been administered, and this therapy was withdrawn. It was considered of interest to investigate the B-cell function in nondiabetic subjects after such a long period of insulin therapy. Since it has been suggested that the presence of insulin antibodies may be a factor in the development of diabetic microangiopathy,¹ we also searched for evidence of this condition.

Report of Cases

CASE 1.—

In 1946, a 23-year-old man was found to have glucosuria, 1.5% to 4.0%; there was no ketonuria. Despite the absence of classic symptoms of diabetes mellitus and the recording of one normal glucose value, treatment was given, consisting of diet and administration of . . . [Full Text PDF of this Article]

Author Affiliations
From the Departments of Medicine, Falu Hospital, Falun, Sweden, and Karolinska Institute, Huddinge Hospital, Stockholm.

Footnotes
Reprint requests to Department of Medicine, Falu Hospital, S-791 00 Falun, Sweden (Dr Asplund).

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