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Kallmann's Syndrome Associated With Atrial Septal Defect
Cedo Dimitrovski, MD;
Aleksandar Plaseski, MD;
Milco Bogoev, MD;
Samuel Sadikario, MD
JAMA. 1982;248(11):1358-1359.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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THE EXISTENCE of hypogonadism with anosmia was first described in an autopsy case in 1856 by Maestre de San Juan.1 In 1944, Kallmann et al2 suggested sex-linked inheritance of hypogonadotropic hypogonadism with anosmia and noted occurrence of harelip, cleft palate, and craniofacial asymmetry. Since then, other clinical cases associated with various skeletal, ophthalmic, urogenital, and cardiovascular abnormalities have been reported.3-5
This article reports an association of Kallmann's syndrome with atrial septal defect (ASD)-type ostium secundum.
Report of a Case
A 22-year-old male student was admitted to our clinic because of great concern about his small penis and inadequate masculinization. He had never shaved or ejaculated. There was a history of lifelong insensitivity to common odors but no family history of hypogonadism, sterility, anosmia, or cardiovascular disorder.
Physical examination showed a eunuchoidal man with some increased adipose tissue over the abdomen and hips. His height was 173 cm
. . . [Full Text PDF of this Article]
Author Affiliations
From the Department of Endocrinology, University of Skopje Medical Faculty, Skopje, Yugoslavia.
Footnotes
Reprint requests to Kej 13 Noemvri 14/16, 91000 Skopje, Yugoslavia (Dr Dimitrovski).
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