This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Manfred Blum, MD; Daniel F. Roses, MD; Noel Cohen, MD
New York University Medical Center New York

JAMA. 1982;248(8):924.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

The report by Chandrasoma and Janssen (1982;247:1406) of a thyroglossal cyst lined by gastric epithelium is intriguing from an embryologic and a clinical perspective. However, we wish to indicate that thyroglossal cysts are not "universally benign" as claimed.

The literature contains reference to some 90 examples of carcinoma in the thyroglossal tract, mostly of the papillary type.^1-5 In as many as 25% of cases, carcinoma may be present elsewhere in the thyroid gland.³ The prognosis for patients with this neoplasm appears to be excellent,² but recently a fatality due to anaplastic carcinoma that arose in a thyroglossal duct remnant was reported.⁵ Since seven patients with this disorder were observed in our institution during the past ten years² (additional manuscript submitted for publication), it is possible to speculate that a malignant neoplasm in a thyroglossal duct actually may not be terribly rare. . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?