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Elizabeth Rasche González

JAMA. 1983;249(4):445-446.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The suspicion that chronic anovulation with unopposed estrogen production increases a woman's risk of developing breast cancer has now been confirmed—in part—by a large-scale, retrospective epidemiologic study.

Such a patient is not at increased risk for premenopausal carcinoma of the breast, but is at significantly increased risk for postmenopausal carcinoma.

For that reason, proposes Carolyn B. Coulam, MD, of the Mayo Clinic, Rochester, Minn, young women with chronic anovulation syndrome should be treated early and older women with a history of premenopausal anovulation should be apprised of their statistically increased risk of developing breast cancer.

Coulam, a consultant at the Mayo Clinic and director of its Reproductive Endocrinology and Infertility Clinic, reported her findings at the recent clinical congress of the American College of Surgeons (ACS) in Chicago. In the study, she and colleague John F. Annegers, PhD, currently affiliated with the University of Texas Medical School . . . [Full Text PDF of this Article]

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