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  Vol. 250 No. 22, December 9, 1983 TABLE OF CONTENTS
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Neonatal Herpes: How Can It Be Prevented?

Nancy J. Binkin, MD, MPH; E. Russell Alexander, MD

JAMA. 1983;250(22):3094-3095.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Neonatal herpes is a disease with serious consequences. Even with vidarabine therapy, more than one third of affected infants will die and another one fourth will have some degree of neurological sequelae.1 Neonatal herpes can be caused by either type 1 or type 2 herpes simplex virus (HSV) and may be acquired during delivery or postnatally. A majority of cases, however, are caused by HSV-2 and are acquired during delivery through contact with an infected genital tract. Women with primary infection are at higher risk of transmitting the virus to their offspring during delivery than those with recurrent infection.2,3

Genital HSV infections seem to be increasing among the adult population in the United States. No national data exist on incidence or prevalence. However, a recent study from Olmsted County, Minnesota, reported a rise in incidence from 12.5 per 100,000 persons in 1965 to 1969 to 82.3 per 100,000 . . . [Full Text PDF of this Article]


Author Affiliations

Center for Health Promotion and Education Centers for Disease Control; Center for Preventive Services Centers for Disease Control Atlanta



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