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Epinephrine for Treatment of Anaphylactic Shock
Eric M. Barach, PA;
Richard M. Nowak, MD;
Tennyson G. Lee, MD;
Michael C. Tomlanovich, MD
JAMA. 1984;251(16):2118-2122.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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SYSTEMIC anaphylactic shock is a medical emergency caused by the release of chemical substances in response to an antigenic stimulus in a previously sensitized person. This stimulus may be food, drugs, blood products, insect venom, or exposure to pollens. Epinephrine has been considered the drug of choice in this emergency. A patient was initially seen in systemic anaphylactic shock secondary to a bee sting and was treated with intravenous (IV) epinephrine. Although the dose used was within the acceptable range advocated by many authors, there were serious early and delayed consequences associated with its use. This led to a review of the literature concerning the use of IV epinephrine in treating systemic anaphylactic shock. The potential problems inherent in uncritically accepting the current recommendations for therapy with IV epinephrine are discussed.
Report of a Case
A 34-year-old previously healthy man was admitted to the emergency department with complaints of rapid
. . . [Full Text PDF of this Article]
Author Affiliations
From the Department of Emergency Medicine (Mr Barach and Drs Nowak and Tomlanovich) and the Division of Cardiology (Dr Lee), Henry Ford Hospital, Detroit.
Footnotes
Reprint requests to Department of Emergency Medicine, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202 (Dr Nowak).
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