This Article  • References  • Full text PDF  • Correction  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Council on Scientific Affairs

JAMA. 1984;251(18):2398-2407.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SURGERY, radiation, and chemotherapy have all been individually demonstrated to be effective anticancer treatments under various circumstances, but surgery and radiation therapy remain the major treatment methods for the local control of most solid neoplasms. Because local treatment failure is still a too frequent result of these regional approaches used individually, the combination of these two local therapies is being evaluated and exploited by oncologists.

Subsequent treatment failure from late micrometastases, clinically undetected at the time of initial local treatment, is a frequent phenomenon with many human cancers. The addition of adjuvant chemotherapy at the time of initial local regional treatment has been shown to be effective in managing several pediatric cancers and some adult neoplasms as well. Other potentially beneficial additions to combined therapies include hormonal therapy, biologic response modifiers, hyperthermia, monoclonal antibodies, and interferon. Early results in many of these areas have lent additional encouragement to the concept . . . [Full Text PDF of this Article]

Author Affiliations
From the Council on Scientific Affairs, Division of Scientific Activities, American Medical Association, Chicago.

Footnotes
Report F of the Council on Scientific Affairs, adopted by the House of Delegates of the American Medical Association at the 1983 Annual Meeting.

This report is not intended to serve as a standard of medical care; standards of medical care that are determined locally and are constantly subject to change are established on the basis of all the several facts of the individual case.

Reprint requests to Division of Scientific Activities, Council on Scientific Affairs, American Medical Association, 535 N Dearborn St, Chicago, IL 60610 (Richard J. Jones, MD).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?