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Cholesterol and Coronary Heart Disease: A Perspective
Shahbudin H. Rahimtoola, MD
JAMA. 1985;253(14):2094-2095.
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In this issue of THE JOURNAL is the statement of the National Institutes of Health Consensus Development Conference on lowering blood cholesterol1; their recommendations are reasonable and can be supported. However, it is important at this point to review certain related issues.
There is no doubt that elevated blood cholesterol levels and other "high-risk" factors, such as cigarette smoking, high blood pressure, obesity, physical inactivity, male sex, stressful lifestyle, and strong family history, are associated with an increased risk of development of coronary artery disease. However, even if all the recognized risk factors were eliminated except for the male sex, coronary atherosclerosis and death from coronary artery disease will not disappear. Therefore, it needs to be recognized that we do not yet know the cause(s) of coronary atherosclerosis2 and there is a need for continued research to discover the cause(s) and specific treatment of coronary atherosclerosis.
The recent interest,
. . . [Full Text PDF of this Article]
Author Affiliations
University of Southern California School of Medicine Los Angeles
Footnotes
Address editorial communications to the Editor, 535 N Dearborn St, Chicago, IL 60610.
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