
A Case of Stadol Dependence
William S. Evans, MD;
James N. Bowen, DO;
Frank L. Giordano, MD;
Bruce Clark, PharmD
Tripler Army Medical Center Tripler AMC, Hawaii
JAMA. 1985;253(15):2191-2192.
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To the Editor.—
Stadol (butorphanol tartrate) was introduced in 1978 as a potent synthetic opiate agonist-antagonist indicated for the relief of moderate to severe pain. The official package circular reproduced in the Physician's Desk Reference notes that, "even though Stadol has a low physical dependence liability, care should be taken that individuals who may be prone to drug abuse are closely supervised." Stadol is handled as a nonscheduled drug and only routine security measures are taken with its storage and distribution. A recent case that we treated led us to question the wisdom of this policy.
Report of a Case.—
The patient was a staff member of our institution who underwent surgical excision of a salivary gland approximately eight months before admission to our service. The patient's postoperative pain was treated with meperidine hydrochloride (Demerol) given in 50-mg doses intramuscularly every six hours for a total of three doses. The
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