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Eve Scopelitis, MD; Myriam Perez, MD; Joseph J. Biundo, Jr, MD
Louisiana State University Medical Center New Orleans

JAMA. 1985;253(15):2194.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In Reply.—

We appreciate the comments of Drs Calmes and Bartholomew. Systemic lupus erythematosus was considered, but, the clinical picture of the two patients, along with the absence of serological abnormalities, excluded this diagnosis.

We are familiar with the entity of ANA-negative SLE and its strong association with anti-SSA (or Ro) antibodies.^1,2 Serum samples from both patients were tested for specific ANA, including anti-SSA, and were found to be negative on multiple occasions. Nevertheless, the presence of anti-SSA antibodies is not restricted to SLE. In a recent study, these antibodies were demonstrated in the serum of patients with a variety of connective-tissue diseases, including two patients with otherwise typical Still's disease (one adult and one child).³

The dermatologic manifestations of Still's disease are very different from those of subacute cutaneous lupus. As in the two cases presented, the rashes of Still's disease are transient and nonphotosensitive, while those . . . [Full Text PDF of this Article]

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