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Unexplained Elevation of Serum Alkaline Phosphatase Levels-Reply
Peter G. Steinherz, MD;
Laurel J. Steinherz, MD
Memorial Sloan-Kettering Cancer Center New York
JAMA. 1985;253(18):2646.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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In Reply.—
The case history described by Dr Dodds and those sent to us directly by other readers of THE JOURNAL since publication of the article highlight the need for increased awareness of the entity by clinicians.
The question as to the source of the enzyme and the stimulus for its brief hypersecretion is still unresolved. Unfortunately, details are not available in the references cited by Dr Dodds, as these consist of brief anecdotal case reports or collections of few cases. Their own authors state at times that their comments regarding the source of the enzyme and specific patterns are "speculation."1,2 We cannot, therefore, draw definite conclusions about hyperphosphatasemia from the information available and can only confirm that its occurrence is benign.
. . . [Full Text PDF of this Article]
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